Some cancers are harder to identify than others¹. This is especially true in lung cancer². Differentiating between the various subtypes of lung cancer, even under a microscope, can be a very difficult task^2,3. In one study, up to 40% of squamous or adenocarcinomas of the lung were reclassified when evaluated by a second pathologist².

The methods currently used to diagnose squamous and non-squamous NSCLC have limitations and may be inaccurate^2,4,5. Until recently, no one test was available to help doctors accurately tell whether their patients had squamous or non-squamous NSCLC. miRview™ squamous is a unique kind of test. It uses cutting-edge technology to tell if you have squamous NSCLC or non-squamous NSCLC⁶.

NSCLC is often not found until it starts to cause symptoms7. At this point, it may be very advanced7. It is important to begin the right treatment as soon as you receive a clear diagnosis. miRview™ squamous can differentiate between squamous and non-squamous NSCLC and deliver your diagnosis quickly and accurately. This can help you get the most appropriate treatment right from the start.

1. Yaziji H, Battifora H, Barry TS, et al. Evaluation of 12 antibodies for distinguishing epithelioid mesothelioma from adenocarcinoma: identification of a three-antibody immunohistochemical panel with maximal sensitivity and specificity. Mod Pathol. 2006;19(4):514-523.
2. Stang A, Pohlabeln H, Müller KM, Jahn I, Giersiepen K, Jöckel KH. Diagnostic agreement in the histopathological evaluation of lung cancer tissue in a population-based case-control study. Lung Cancer. 2006;52(1):29-36.
3. Marchevsky AM. Application of immunohistochemistry to the diagnosis of malignant mesothelioma. Arch Pathol Lab Med. 2008;132(3):397-401.
4. Perelman M, Rosenwald S, Spector Y, et al. MicroRNA biomarkers for differential diagnosis of lung tumors. Presented at: United States and Canadian Academy of Pathology Annual Meeting; March 7-13, 2009; Boston, MA. Abstract 1630.
5. Field RW, Smith BJ, Platz CE, et al. Lung cancer histologic type in the surveillance, epidemiology, and end results registry versus independent review. J Natl Cancer Inst. 2004;96(14):1105-1107.
6. Rosenfeld N, Aharonov R, Meiri E, et al. MicroRNAs accurately identify cancer tissue origin. Nat Biotechnol. 2008;26(4):462-469.
7. Detailed guide: lung cancer―non-small cell: how is non-small cell lung cancer diagnosed? American Cancer Society Web site. http://www.cancer.org/docroot/CRI/content/CRI_2_4_3x_How_Is_Non-Small_Cell_Lung_Cancer_Diagnosed.asp?rnav=cri. Updated October 24, 2008. Accessed February 23, 2009.