FAQs

Frequently Asked Questions (FAQ)

Q: What is CUP?
A: CUP stands for cancer of unknown primary. It is a kind of cancer that is found when the disease has spread to one or more sites and doctors are not sure where it started1.
Q: How is CUP currently diagnosed?
A: CUP has always spread beyond the place where it started by the time it is found. If it had been found early, it would not be CUP.
In an attempt to find the place where the cancer started, the doctor will first take a medical history and do a physical exam. Sometimes these basic steps can suggest the source of the cancer. If not, other tests such as imaging scans and blood tests may help narrow the search. However, it is important to keep in mind that you are not guaranteed a specific diagnosis by taking these tests.
It is in your best interest to find out which test(s) your doctor plans to use to diagnose your cancer. A new kind of tests called miRview® mets and miRview® mets2 may be able to help your doctor determine exactly where your cancer started, regardless of whether or not you have been officially diagnosed as a CUP patient. This is important because the origin of your cancer can have a big impact on your treatment plan. If your doctor is not familiar with miRview® mets, click on the button at left (right?) to print out information to bring to your next appointment.
Q: Why were the miRview® mets tests developed?
A: miRview® mets was developed to give doctors a way to determine the primary tumor site of metastatic tumors. This information helps doctors develop more effective treatment plans. miRview® mets2 is a second generation version of miRview® mets and includes and expanded panel of 42 identifiable tumors
Q: How do the miRview® mets tests work?
A: the miRview® mets use tiny bits of material called microRNAs to determine the primary tumor site.
Q: Why do I need the miRview® mets tests?
A: In most cases, the miRview® mets tests can determine the primary origin of your cancer. Once your doctor knows the primary origin of your cancer, he or she can decide which treatment(s) will work best for you.
Q: How does my doctor perform the test?
A: Your doctor will send a small section of your biopsy to Rosetta Genomics for evaluation.
Q: How long does it take to get the results of the test?
A: Your doctor will receive the miRview® mets tests results about 10 business days after he or she sends in the sample.
Q: What does Rosetta Genomics do?
A: Rosetta Genomics is focused on developing tests based on a recently discovered family of genes called microRNAs. The tests developed by Rosetta Genomics are used primarily in cancer patients.
Q: How long has Rosetta Genomics been in business?
A: Nine years. Rosetta Genomics was founded in 2000.
Q: Where is Rosetta Genomics based?
A: Rosetta Genomics is an international company with a laboratory in Philadelphia, Pennsylvania, and a research and development center based in Rehovot, Israel.

  1. Overview: cancer of unknown primary: what is cancer of unknown primary? American Cancer Society Web site. Updated November 30, 2008. Accessed February 25, 2009.